DONATE TODAY
To Increase Patient Access
End Brain Cancer Mobile App to download your number one tool for navigating this disease.

The goal of SonALAsense is to turn cancer 
patients into cancer survivors.

Clinical Trials Now Recruiting
SDT-201 ELIGIBILITY FORM
Clinical Trial for DIPG (Pediatrics)
SDT-202 ELILGIBILITY FORM
Clinical trial for recurrent glioblastoma (rGBM)
TREATING CANCER DIFFERENTLY
SonALAsense was founded to create hope in the face of despair with Sonodynamic Therapy (SDT), a non-invasive way to treat and eradicate deadly cancers like High-Grade Gliomas (HGG) that typically require debilitating brain surgery that often leads to tumor recurrence.

SDT uses SONALA-001 and an MR-guided focused ultrasound device, a true drug-device combination. Both drug and device are required for a therapeutic effect. The phase 0/1 clinical trial in Recurrent HGG gives us hope as we pursue our mission.

Working to make life more normal 
for patients.

SonALAsense is committed to providing hope in the face of despair by developing sonodynamic therapy (SDT) to be a safe and effective treatment for cancer.

SonALAsense’s SDT is a noninvasive targeted combination of SONALA-001 (Intravenous Aminolevulinic Acid) and MR-guided focused ultrasound. 


We are the first SDT company in clinical trials.

Please call our EBCI Clinical Research Coordinator
& Patient Navigator at 425-436-8688 w/questions.

Core Goals of SonALAsense

PURSUE
INNOVATION
INSTILL
HOPE
IMPROVE
LIFE

Providing hope for patients.

LEARN MORE ABOUT SONALASENSE

"The Reason For Our Commitment"

By SonALAsense

Glioma cells, bladder cancer cells, skin cancer cells and other cancer cells have been shown to have a special need for a compound called aminolevulinic acid (ALA). When these cancer cells were given large amounts of ALA, they glowed pink when exposed to blue light. This finding led to ALA becoming a commercially available product (Gleolan®) that is used as a visual aid by neurosurgeons to help them identify and surgically remove aggressive brain tumors. Another ALA product (Cysview®) is used by urologists to identify bladder cancer cells that are otherwise difficult to find.

We knew more than 30 years ago that the same byproduct of ALA that made cancer cells glow could be activated to kill the cancer 
cells using high-energy light in a process called photodynamic therapy (PDT, see Our Science). PDT has a rapid onset of action and minimal effects on normal brain cells. Unfortunately, as we tried to develop PDT to treat brain tumors we found that it required invasive and complex light delivery techniques making it difficult to develop. When it was reported that the same PDT process could be activated noninvasively using MR-guided focused ultrasound to produce light within the brain (sonodynamic therapy, SDT), we founded SonALAsense to bring this new, noninvasive cancer-specific treatment to patients as soon as possible.
SonALAsense is developing SDT to treat multiple types of solid tumors.
LEARN MORE ABOUT SDT
Clinical Trials Now Recruiting
SDT-201 ELIGIBILITY FORM
Clinical Trial for DIPG (Pediatrics)
SDT-202 ELILGIBILITY FORM
Clinical trial for recurrent glioblastoma (rGBM)
Please call our EBCI Clinical Research Coordinator
& Patient Navigator at 425-436-8688 w/questions.

ENDBRAINCANCER INITIATIVE | CHRIS ELLIOTT FUND

Enhancing patient outcomes by expanding FDA-approved treatment modalities and fueling research in the pharma/bio/life sciences, device & diagnostic industries and by closing the existing GAP from initial diagnosis to IMMEDIATE AND EXPANDED ACCESS to specialists, researchers, advanced & innovative treatments, clinical trials and critical care with the ultimate goal of improving patient outcomes through updating and improving WHO & NCCN Guidelines and clinical practices related to Standard of Care for brain cancer patients.

TAX ID:26-2185614
DONATE
corporate partners
upcoming events
resources
About us
envelopephonemap-markerpointer-right
linkedin facebook pinterest youtube rss twitter instagram facebook-blank rss-blank linkedin-blank pinterest youtube twitter instagram